Ethanol → 2(1H)-Quinoxalinone

HRID 493976

반응식

HRID 493976 반응식
[C:1]1([NH2:8])[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[NH2:7].[CH3:9][CH2:10][OH:11]>>[NH:7]1[C:2]2[C:1](=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:8]=[CH:9][C:10]1=[O:11]

참가 물질

3

반응물 2

HCID 702EthanolHCID 7243O-Phenylenediamine

생성물 1

HCID 145262(1H)-Quinoxalinone

실험 절차

A mixture of the 1,2-phenylene-diamine derivative (1 g) and the 2-oxo-carboxylic acid derivative (1 eq) in dry EtOH (35 mL) was stirred at reflux for 2 h under nitrogen. After cooling, the EtOH was evaporated to give a crude brown solid. Recrystallisation from EtOH gave the desired quinoxalin-2-one derivative.

후처리

  1. temperatureat reflux for 2 h under nitrogen
  2. temperatureAfter cooling
  3. customthe EtOH was evaporated
  4. customto give a crude brown solid
  5. customRecrystallisation from EtOH

출처 및 근거

ORD 기록
ord-e11bf6e15ac14fa9a03e91a18f60a7dd
출처 데이터셋
uspto-grants-2009_05
특허 번호
US07538109B2

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