Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
7-Aminoquinoline → 6-Chloro-N-quinolin-7-yl-nicotinamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 7-Aminoquinoline | HCID 11377 | — |
| 반응물 | 6-Chloronicotinic acid | HCID 79222 | — |
| 생성물 | 6-Chloro-N-quinolin-7-yl-nicotinamide | HCID 44578987 | — |
반응 단계
Using the procedure outlined in Example 45, the title compound was prepared from 7-aminoquinoline (D55) (213 mg, 1.48 mmol) and 6-chloronicotinic acid (279 mg, 1.77 mmol) as a cream solid (405 mg). 1H NMR (250 MHz, CDCl3) δ (ppm): 8.94 (m, 2H), 8.24 (m, 2H), 8.16 (d, 1H), 8.14 (br.s, 1H), 8.01 (dd, 1H), 7.87 (d, 1H), 7.51 (d, 1H), 7.39 (dd, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07538121B2 |
| 출처 데이터셋 | uspto-grants-2009_05 |
| ORD ID | ord-727e4c33b2344710ad301c95ebdd7540 |
| 출처 메모 | uspto-grants-2009_05 |