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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 494238생성일: 2026년 10월 25일

2,6-Dimethylphenylboronic acid → 2',6'-Dimethyl-N-quinolin-7-yl-1,1'-biphenyl-4-carboxamide

https://huagongshe.com/reaction/494238

반응식

참여 물질

역할이름HCID투입량
반응물2,6-Dimethylphenylboronic acidHCID 583322—
반응물4-bromo-N-quinolin-7-ylbenzamideHCID 831408—
생성물2',6'-Dimethyl-N-quinolin-7-yl-1,1'-biphenyl-4-carboxamideHCID 57682675—

반응 단계

Using the procedure outlined in Example 58, the title compound was prepared from 4-bromo-N-quinolin-7-ylbenzamide (Example 82) (50 mg, 0.153 mmol) and 2,6-dimethyl-phenylboronic acid (25 mg, 0.17 mmol) as a white solid. 1H NMR (400 MHz, CDCl3) δ (ppm): 8.92 (dd, 1H), 8.20 (d, 1H), 8.14 (m, 3H), 8.02, (d, 2H), 7.87 (d, 1H), 7.37 (dd, 1H), 7.34 (d, 2H), 7.21 (t, 1H), 7.14 (d, 2H), 2.05 (s, 6H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07538121B2
출처 데이터셋uspto-grants-2009_05
ORD IDord-bf000f578d3d41449fd2250791ab27eb
출처 메모uspto-grants-2009_05