2-Methylquinolin-7-amine → HCID 57682716, 화합물

반응식

[NH2:1][C:2]1[CH:11]=[C:10]2[C:5]([CH:6]=[CH:7][C:8]([CH3:12])=[N:9]2)=[CH:4][CH:3]=1.[CH3:13][C:14]1[N:19]=[C:18]([C:20]2[CH:28]=[CH:27][C:23]([C:24](O)=[O:25])=[CH:22][CH:21]=2)[CH:17]=[CH:16][CH:15]=1>>[CH3:12][C:8]1[CH:7]=[CH:6][C:5]2[C:10](=[CH:11][C:2]([NH:1][C:24](=[O:25])[C:23]3[CH:27]=[CH:28][C:20]([C:18]4[CH:17]=[CH:16][CH:15]=[C:14]([CH3:13])[N:19]=4)=[CH:21][CH:22]=3)=[CH:3][CH:4]=2)[N:9]=1

참가 물질

반응물 2

HCID 4596552-Methylquinolin-7-amine

HCID 534263364-(6-Methylpyridin-2-yl)benzoic acid

생성물 1

HCID 57682716HCID 57682716, 화합물

실험 절차

Using the procedure outlined in Example 56, the title compound was prepared from 7-amino-2-methylquinoline (D66) (33 mg, 0.21 mmol) and 4-(6-methyl-2-pyridyl)benzoic acid (D29) (47 mg, 0.25 mmol) as an off-white solid. MS (ES): MH+ 354, M-H+ 352.

출처 및 근거

ORD 기록: ord-2c8690203ecb4ecfbc77ecef881fce23
출처 데이터셋: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07538121B2

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