Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → HCID 178418666, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Triethylamine hydrochloride | HCID 11130 | — |
| 반응물 | Sodium Azide | HCID 33557 | — |
| 반응물 | 4-Benzyloxybenzonitrile | HCID 561371 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | HCID 178418666 | HCID 178418666 | 98.1% |
반응 단계
A mixture of 285 g of the nitrile, 262.5 g triethylamine hydrochloride and 124 g of sodium azide in 1.5 L of DMF under nitrogen was stirred under reflux for 18 hrs. The reaction mixture was cooled to room temperature, poured into 4 L of cold water and acidified with 3N HCl. The resulting white solid was collected, washed with water and dried at 60° C. in vacuo for 48 hrs to give 337 g of 5-(4-benzyloxyphenyl)tetrazole.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242924 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-da4ba2e333534753ac71b51a2ea124e5 |
| 출처 메모 | uspto-grants-1993_09 |