Methyl 2-phenyl-2-propylpentanoate → 2-(4-Fluorophenyl)-2,5-dimethylhexanoic acid

반응식

[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]([CH3:18])([CH2:13][CH2:14][CH:15]([CH3:17])[CH3:16])[C:9]([O:11]C)=[O:10])=[CH:4][CH:3]=1.C1(C(CCC)(CCC)C(OC)=O)C=CC=CC=1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]([CH3:18])([CH2:13][CH2:14][CH:15]([CH3:16])[CH3:17])[C:9]([OH:11])=[O:10])=[CH:6][CH:7]=1

참가 물질

반응물 2

HCID 11658708Methyl 2-phenyl-2-propylpentanoate

HCID 68872679Methyl 2-(4-fluorophenyl)-2,5-dimethylhexanoate

생성물 1

HCID 688699802-(4-Fluorophenyl)-2,5-dimethylhexanoic acid

실험 절차

The title compound was prepared according to the procedure of Example 1C, substituting the compound of Example 22B for the compound of Example 1B. 1H NMR (300 MHz, CDCl3): δ 0.86 (t, J=6.43 Hz, 6 H) 1.05 (m, 2 H) 1.51 (m, 4 H) 1.96 (m, 2 H) 7.02 (m, 2 H) 7.34 (m, 2 H).

출처 및 근거

ORD 기록: ord-2a168cabdfa8437baeffe0a8050076b3
출처 데이터셋: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07538105B2

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