Ethyl 1-hydroxy-3-oxo-4,4-dipropyl-3,4-dihydro-2-naphthalenecarboxylate → 1,1-dipropyl-4-hydroxy-2(1H)-naphthalenone

HRID 494606노트

반응식

HRID 494606 반응식
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[C:5]([CH2:15][CH2:16][CH3:17])([CH2:12][CH2:13][CH3:14])[C:4](=[O:18])[C:3]=1C(OCC)=O.C(C1(CCCC)C2C(=CC=CC=2)C(O)=C(C(OCC)=O)C1=O)CCC>>[CH2:15]([C:5]1([CH2:12][CH2:13][CH3:14])[C:6]2[C:11](=[CH:10][CH:9]=[CH:8][CH:7]=2)[C:2]([OH:1])=[CH:3][C:4]1=[O:18])[CH2:16][CH3:17]

참가 물질

3

반응물 2

HCID 54724640Ethyl 1-hydroxy-3-oxo-4,4-dipropyl-3,4-dihydro-2-naphthalenecarboxylateHCID 68871457Ethyl 4,4-dibutyl-1-hydroxy-3-oxo-3,4-dihydro-2-naphthalenecarboxylate

생성물 1

HCID 688716431,1-dipropyl-4-hydroxy-2(1H)-naphthalenone

실험 절차

The title compound was prepared according the procedure of Example 5B, substituting the product of Example 1F for the product of Example 4F. 1H NMR (300 MHz, CDCl3) δ ppm 0.55 (m, 2H) 0.67 (m, 4.8H) 0.79 (m, 1.2H) 0.98 (m, 2H) 1.78 (m, 2H) 2.19 (m, 2H) 3.69 (s, 0.4H) 6.13 (s, 0.8H) 7.41 (m, 2H) 7.56 (m, 0.8H) 7.67 (m, 0.2H) 8.07 (m, 0.2H) 8.13 (m, 0.8H).

출처 및 근거

ORD 기록
ord-69460d1c5c9648fda6fff1fdc8502782
출처 데이터셋
uspto-grants-2009_05
특허 번호
US07538105B2

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