1,5-Dibromopentane → 6-(5-Bromo-pentyloxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester

HRID 49473

반응식

HRID 49473 반응식
[C:1]([O:5][C:6]([N:8]1[C:17]2[C:12](=[CH:13][C:14]([OH:18])=[CH:15][CH:16]=2)[CH2:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[Br:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24]Br>>[C:1]([O:5][C:6]([N:8]1[C:17]2[C:12](=[CH:13][C:14]([O:18][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][Br:19])=[CH:15][CH:16]=2)[CH2:11][CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 2

HCID 81001,5-DibromopentaneHCID 53408427Tert-butyl 6-hydroxy-3,4-dihydroquinoline-1(2H)-carboxylate

생성물 1

HCID 695149026-(5-Bromo-pentyloxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester수율 63%

실험 절차

In analogy to example 2.2, 6-Hydroxy-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester and 1,5-dibromopentane were converted to yield 6-(5-Bromo-pentyloxy)-3,4-dihydro-2H-quinoline-1-carboxylic acid tert-butyl ester (63%) as colorless oil, MS: 397 (M, 1Br);

출처 및 근거

ORD 기록
ord-3ccff50af97f4bf7a926d30851c2e665
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06706751B2

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