Methanesulfonyl chloride → 3-[5-(3-Cyanophenyl)-1-benzofuran-2-yl]propyl methanesulfonate

HRID 494893노트

반응식

HRID 494893 반응식
[OH:1][CH2:2][CH2:3][CH2:4][C:5]1[O:6][C:7]2[CH:13]=[CH:12][C:11]([C:14]3[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=3)[C:17]#[N:18])=[CH:10][C:8]=2[CH:9]=1.[CH3:22][S:23](Cl)(=[O:25])=[O:24]>>[CH3:22][S:23]([O:1][CH2:2][CH2:3][CH2:4][C:5]1[O:6][C:7]2[CH:13]=[CH:12][C:11]([C:14]3[CH:21]=[CH:20][CH:19]=[C:16]([C:17]#[N:18])[CH:15]=3)=[CH:10][C:8]=2[CH:9]=1)(=[O:25])=[O:24]

참가 물질

3

반응물 2

HCID 31297Methanesulfonyl chlorideHCID 222746073-[2-(3-Hydroxypropyl)-1-benzofuran-5-yl]benzonitrile

생성물 1

HCID 222745843-[5-(3-Cyanophenyl)-1-benzofuran-2-yl]propyl methanesulfonate

실험 절차

The product from Example 170B and methanesulfonyl chloride is processed as described in Example 112D to provide the title compound.

출처 및 근거

ORD 기록
ord-2f5dc75cfcd249d8a2cb54057f52c819
출처 데이터셋
uspto-grants-2009_05
특허 번호
US07538138B2

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