Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → Ethyl 2-(piperidin-4-yl)acetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | Ethyl pyridine-4-acetate | HCID 736321 | — |
| 촉매 | Platinum oxide (PtO) | HCID 82844 | — |
| 용매 | Ethanol | HCID 702 | — |
| 용매 | HCID 178418361 | HCID 178418361 | — |
| 생성물 | Ethyl 2-(piperidin-4-yl)acetate | HCID 2760465 | 162.3% |
반응 단계
16.5 g (0.1 mol) Ethyl 4-pyridylacetate, 8.4 mL (0.1 mol) 12N hydrochloric acid and 2.5 g platinum oxide were dissolved in absolute ethanol and hydrogenated at 40 psi hydrogen on a Parr shaker. After 1 hour, the contents of the vessel were filtered and concentrated in vacuo yielding 27.79 g of ethyl 4-piperidinylacetate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242924 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-4bf57d14da074ba286dc99dcf47db4ab |
| 출처 메모 | uspto-grants-1993_09 |