Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1'-Carbonyldiimidazole → 1-(1-Azabicyclo[2.2.2]oct-3-yl)-3-(3-chlorophenyl)-imidazolidin-2-one hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 반응물 | N-(1-azabicyclo[2.2.2]oct-3 yl)-N'-(3-chlorphenyl)-1,2-diaminoethane | HCID 10492977 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 1-(1-Azabicyclo[2.2.2]oct-3-yl)-3-(3-chlorophenyl)-imidazolidin-2-one hydrochloride | HCID 20081926 | — |
반응 단계
To a stirred solution of N-(1-azabicyclo[2.2.2]oct-3 yl)-N'-(3-chlorphenyl)-1,2-diaminoethane (2.7 g; 0.0097 moles) in anhydrous tetrahydrofuran (10 ml), N,N-carbonyldiimidazole (2.04 g; 0.0125 moles) is added.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242929 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-14c963ad2f0d4f1db8384f9ea0e1f629 |
| 출처 메모 | uspto-grants-1993_09 |