Acetone → 2,4-Bis(allyloxy)-1-ethylbenzene

HRID 495306

반응식

HRID 495306 반응식
[CH2:1]([C:3]1[CH:9]=[CH:8][C:6]([OH:7])=[CH:5][C:4]=1[OH:10])[CH3:2].C(=O)([O-])[O-].[K+].[K+].[CH2:17](Br)[CH:18]=[CH2:19].[CH3:21][C:22]([CH3:24])=O>>[CH2:17]([O:10][C:4]1[CH:5]=[C:6]([O:7][CH2:24][CH:22]=[CH2:21])[CH:8]=[CH:9][C:3]=1[CH2:1][CH3:2])[CH:18]=[CH2:19]

참가 물질

5

반응물 4

HCID 180AcetoneHCID 7841Allyl bromideHCID 11430Potassium CarbonateHCID 179274-Ethylresorcinol

생성물 1

HCID 45498682,4-Bis(allyloxy)-1-ethylbenzene수율 95%

실험 절차

4-Ethylresorcinol (10 g, 73 mmol) was dissolved in acetone (250 mL), and potassium carbonate (30 g, 220 mmol) and allyl bromide (15 mL, 170 mmol) were added thereto and heated under reflux for 4 hours. The reaction mixture was cooled to room temperature, then filtered through Celite, and the filtrate was concentrated under reduced pressure. The resulting residue was purified through silica gel column chromatography (ethyl acetate/n-hexane=1/9) to obtain 2,4-bis(allyloxy)-1-ethylbenzene (15 g, 95%).

후처리

  1. temperatureheated
  2. temperatureunder reflux for 4 hours
  3. filtrationfiltered through Celite
  4. concentrationthe filtrate was concentrated under reduced pressure
  5. customThe resulting residue was purified through silica gel column chromatography (ethyl acetate/n-hexane=1/9)

출처 및 근거

ORD 기록
ord-a972cf91d66a4022bfea1f8451cc6534
출처 데이터셋
uspto-grants-2009_05
특허 번호
US07538241B2

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