(2-Nitrophenyl)hydrazine → 3-Chloro-5-(trifluoromethyl)-2-pyridinecarbaldehyde 2-(2-nitrophenyl)hydrazone

HRID 495395

반응식

HRID 495395 반응식
[Cl:1][C:2]1[C:3]([CH:12]=O)=[N:4][CH:5]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:7]=1.[N+:14]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[NH:23][NH2:24])([O-:16])=[O:15]>C(O)C>[N+:14]([C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][C:18]=1[NH:23][N:24]=[CH:12][C:3]1[C:2]([Cl:1])=[CH:7][C:6]([C:8]([F:11])([F:10])[F:9])=[CH:5][N:4]=1)([O-:16])=[O:15]

참가 물질

4

반응물 2

HCID 3314739(2-Nitrophenyl)hydrazineHCID 220187903-Chloro-5-(trifluoromethyl)picolinaldehyde

생성물 1

HCID 686150543-Chloro-5-(trifluoromethyl)-2-pyridinecarbaldehyde 2-(2-nitrophenyl)hydrazone

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A mixture of 3-chloro-5-(trifluoromethyl)pyridine-2-carboxaldehyde (1.05 g) and 2-nitrophenylhydrazine (0.76 g) in ethanol (75 ml) was heated at reflux for 2.5 hours and then allowed to cool to room temperature overnight. The resulting orange solid was isolated by filtration and recrystallised (petrol) to afford the title compound as admixture of isomers, m.p. 127-35° C.

후처리

  1. temperaturewas heated
  2. temperatureat reflux for 2.5 hours
  3. customThe resulting orange solid was isolated by filtration
  4. customrecrystallised (petrol)

출처 및 근거

ORD 기록
ord-35658f78fa5c461cbe8d5acfc759eb93
출처 데이터셋
uspto-grants-2005_09
특허 번호
US06939882B1

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