Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-bromobutanimide → 2-(Bromomethyl)-1-chloro-3-methoxybenzene
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-bromobutanimide | HCID 67184 | — |
| 반응물 | 3-Chloro-2-methylanisole | HCID 76749 | — |
| 촉매 | Azobisisobutyronitrile | HCID 6547 | — |
| 용매 | Carbon Tetrachloride | HCID 5943 | — |
| 생성물 | 2-(Bromomethyl)-1-chloro-3-methoxybenzene | HCID 22327443 | 72.7% |
반응 단계
442 g of 2-chloro-6-methoxytoluene are dissolved in 2420 ml of carbon tetrachloride and, together with 516 g of N-bromosuccinimide, heated at reflux for 2 h while 5.8 g of AIBN are added. The solid is filtered off and washed with a small amount of carbon tetrachloride, the filtrate is concentrated, and the residue which remains is fractionated. 483 g of colorless oil are obtained (b.p. 100° C./1.4 mbar, m.p. 44-47° C.).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06939888B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-13db7c02808443b4b1d3ed92957b86fe |
| 출처 메모 | uspto-grants-2005_09 |