Ethylene Glycol → 2-(2-Chloro-4-methoxyphenyl)acetic acid

HRID 495518노트

반응식

HRID 495518 반응식
[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1CC#N.[OH-:13].[K+].[CH2:15]([OH:18])[CH2:16]O>>[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH3:9])[CH:5]=[CH:4][C:3]=1[CH2:16][C:15]([OH:18])=[O:13]

참가 물질

4

반응물 3

HCID 174Ethylene GlycolHCID 14797Potassium HydroxideHCID 22327506(2-Chloro-4-methoxyphenyl)acetonitrile

생성물 1

HCID 42091322-(2-Chloro-4-methoxyphenyl)acetic acid

실험 절차

657 g (purity 75%) of 2-chloro-4-methoxyphenylacetonitrile are reacted with 303 g of potassium hydroxide in 1308 ml of ethylene glycol. 430 g of solid are obtained (m.p.: 83-86° C.).

출처 및 근거

ORD 기록
ord-e7deb3d49ae545458c9fe8cad6862af9
출처 데이터셋
uspto-grants-2005_09
특허 번호
US06939888B2

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