Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Diethyl Ether → N-(cis)-{2-[(aminoacetyl)amino]cyclohexyl}-4-(aminosulfonyl)benzamide hydrogen bromide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Diethyl Ether | HCID 3283 | — |
| 반응물 | Acetic Acid Mixture with Hydrobromic Acid | HCID 21893785 | — |
| 반응물 | Benzyl (cis)-2-[(2-{[4-(aminosulfonyl)benzoyl]amino)cyclohexyl)amino]-2-oxoethylcarbamate | HCID 86587037 | — |
| 생성물 | N-(cis)-{2-[(aminoacetyl)amino]cyclohexyl}-4-(aminosulfonyl)benzamide hydrogen bromide | HCID 68830145 | — |
반응 단계
The material from above benzyl (cis)-2-[(2-{[4-(aminosulfonyl)benzoyl]amino}cyclohexyl)amino]-2-oxoethylcarbamate (217 mg) was dissolved in 30% HBr/AcOH (5 mL) at rt. After 1 h, Et2O was added and the solid was collected to give N-(cis)-{2-[(aminoacetyl)amino]cyclohexyl}-4-(aminosulfonyl)benzamide hydrogen bromide. MS found: (M+H)+=355.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06706712B2 |
| 출처 데이터셋 | uspto-grants-2004_03 |
| ORD ID | ord-f954d0b4badc4c8c9d0a3a32d1b865ff |
| 출처 메모 | uspto-grants-2004_03 |