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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 49582생성일: 2026년 10월 25일

3,5-Bis(trifluoromethyl)benzaldehyde → cis-4-(3,5-Bis-trifluoromethyl-benzylamino)-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2h-quinoline-1-carboxylic acid isopropyl ester

https://huagongshe.com/reaction/49582

반응식

참여 물질

역할이름HCID투입량
반응물3,5-Bis(trifluoromethyl)benzaldehydeHCID 136247—
반응물cis-4-Amino-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2h-quinoline-1-carboxylic acid isopropyl esterHCID 69623683—
생성물cis-4-(3,5-Bis-trifluoromethyl-benzylamino)-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2h-quinoline-1-carboxylic acid isopropyl esterHCID 131723997—

반응 단계

treating said cis-4-amino-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester first with 3,5-bis-trifluoromethyl-benzaldehyde under acidic conditions followed by a reducing agent to form cis-4-(3,5-bis-trifluoromethyl-benzylamino)-2-ethyl-6-trifluoromethyl-3,4,-dihydro-2H-quinoline-1-carboxylic acid isopropyl ester;

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06706881B2
출처 데이터셋uspto-grants-2004_03
ORD IDord-4255667a58b641f4b7711a7a1e159ac1
출처 메모uspto-grants-2004_03