Ammonia → 5-Amino-3,4-dihydronaphthalen-1(2H)-one

HRID 49659노트

반응식

HRID 49659 반응식
S(=O)(=O)(O)[OH:2].N[C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][CH2:14][CH2:15][C:16]#[N:17].N>>[NH2:17][C:16]1[CH:15]=[CH:14][CH:13]=[C:8]2[C:9]=1[CH2:10][CH2:11][CH2:12][C:7]2=[O:2]

참가 물질

4

반응물 3

HCID 222AmmoniaHCID 1118Sulfuric AcidHCID 184058244-(2-Aminophenyl)butyronitrile

생성물 1

HCID 115065055-Amino-3,4-dihydronaphthalen-1(2H)-one

반응 조건

온도
100 °C

실험 절차

In a 20 ml Schlenk vessel, 1 g of 96% sulfuric acid (9.79 mmol) is added to 100 mg of 4-(2-aminophenyl)butyronitrile (0.62 mmol) under argon. The mixture is heated to 100° C. for 66 h, stirring. After cooling, it is neutralised with aqueous ammonia solution (ice cooling), and the product is then extracted with chloroform and identified using GC.

후처리

  1. temperatureAfter cooling
  2. extractionthe product is then extracted with chloroform

출처 및 근거

ORD 기록
ord-a8a01279e9524fbab2b2b0eb6ff5f636
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06706924B2

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