Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrocodone → Codeine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrocodone | HCID 5284569 | — |
| 반응물 | Thebaine | HCID 5324289 | — |
| 반응물 | Codeinone | HCID 5459910 | — |
| 생성물 | Codeine | HCID 5284371 | — |
| 생성물 | Thebaine | HCID 5324289 | — |
| 생성물 | Codeinone | HCID 5459910 | — |
반응 단계
Hydrocodone has been prepared by reduction of codeinone (Arch. Pharm (1920), 258, 295; J. Am Chem. Soc (1950), 72, 3247, U.S. Pat. No. 5,571,685) or thebaine (DE Pat. No. 441,613). However, since codeinone is obtained by oxidation of codeine in low to moderate yields, and thebaine is a relatively scarce alkaloid, these methods have little practical value.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06946556B1 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-c46228bdbd2a46d990394e87ee0a0f24 |
| 출처 메모 | uspto-grants-2005_09 |