참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Benzoyl chloride | HCID 7412 | — |
| 반응물 | Sodium Hydroxide | HCID 14798 | — |
| 반응물 | Carbamimidic acid, methyl ester, sulfate (1:1) | HCID 169039 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | HCID 69749939 | HCID 69749939 | — |
반응 단계
O-Methylisourea hydrogen sulfate (17.2 g, 0.1 mol) was suspended in water (100 mL) containing NaOH (20 g, 0.5 mol) and the mixture cooled to 5-10° C. The mixture was stirred vigorously as benzoyl chloride (35.15 g, 0.25 mol) was added at such a rate that the reaction temperature did not rise above 15° C. After the last addition, the mixture was stirred for 3 h and the resulting solid collected by vacuum filtration to give N,N′-dibenzoylcarbamimidoic acid, methyl ester.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06946554B2 |
|---|
| 출처 데이터셋 | uspto-grants-2005_09 |
|---|
| ORD ID | ord-cb9abf06b9da49438ab90561af0414ed |
|---|
| 출처 메모 | uspto-grants-2005_09 |
|---|
