Mcl-0042 → HCID 9917300, 화합물
반응식
[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([N:30]2[CH2:35][CH2:34][N:33]([CH3:36])[CH2:32][CH2:31]2)[CH2:9][N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][CH2:18][CH2:19][C:20]3[C:29]4[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=4)[CH:23]=[CH:22][CH:21]=3)[CH2:12][CH2:11]2)=[CH:4][CH:3]=1.[ClH:37].C(OCC)(=O)C>CO>[ClH:37].[ClH:37].[ClH:37].[ClH:37].[F:1][C:2]1[CH:7]=[CH:6][C:5]([CH:8]([N:30]2[CH2:35][CH2:34][N:33]([CH3:36])[CH2:32][CH2:31]2)[CH2:9][N:10]2[CH2:15][CH2:14][N:13]([CH2:16][CH2:17][CH2:18][CH2:19][C:20]3[C:29]4[C:24](=[CH:25][CH:26]=[CH:27][CH:28]=4)[CH:23]=[CH:22][CH:21]=3)[CH2:12][CH2:11]2)=[CH:4][CH:3]=1참가 물질
4
실험 절차
0.30 g of 1-[2-(4-Fluorophenyl)-2-(4-methylpiperazino)ethyl]-4-(4-naphthalen-1-yl-butyl)piperazine was dissolved in 4 ml of methanol, and 1 ml of 4M hydrogen chloride/ethyl acetate solution was added. The solution was concentrated under reduced pressure, and the resulting solid was washed with methanol to give 1-[2-(4-fluorophenyl)-2-(4-methylpiperazino)ethyl]-4-(4-naphthalen-1-yl-butyl)piperazine tetrahydrochloride (0.20 g).