Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Methyl 3-iodobenzoate → Methyl 3-ethylbenzoate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Methyl 3-iodobenzoate | HCID 69258 | — |
| 반응물 | Tributylvinyltin | HCID 81998 | — |
| 반응물 | Potassium Fluoride | HCID 522689 | — |
| 촉매 | HCID 178418397 | HCID 178418397 | — |
| 용매 | Water | HCID 962 | — |
| 용매 | Toluene | HCID 1140 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | Methyl 3-ethylbenzoate | HCID 12430992 | — |
반응 단계
Methyl 3-iodobenzoate (13 g) and vinyl tributyltin (20 g) were dissolved in toluene (100 ml) and tetrakis(triphenylphosphine)palladium (0) (500 mg) added. The solution was heated at reflux with stirring under N2 for 1 day. Potassium fluoride (3 g) in water (50 ml) was added and the reaction mixture was allowed to stir under N2 for 15 minutes. The product was taken up in ethyl acetate and washed with water and then brine (×2). The organic extract was dried (MgSO4) and evaporated in vacuo.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242930 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-2bbab0f4ae63457f992a8d6c141b0c62 |
| 출처 메모 | uspto-grants-1993_09 |