반응식
[CH2:1]([O:3][C:4]1[N:9]=[C:8]([N:10]2[C:14]([NH2:15])=[CH:13][C:12]([CH3:16])=[N:11]2)[CH:7]=[CH:6][CH:5]=1)[CH3:2].[CH2:17](OC1N=C(NN)C=CC=1)[CH3:18].[Cl:28][C:29]1[CH:34]=[CH:33][CH:32]=[C:31](OCC)N=1.IC1C=CC=CC=1C(O)=O>>[CH2:1]([O:3][C:4]1[N:9]=[C:8]([N:10]2[C:14]([NH2:15])=[CH:13][C:12]([CH3:16])=[N:11]2)[CH:7]=[CH:6][CH:5]=1)[CH3:2].[Cl:28][C:29]1[C:34]2[C:33](=[CH:32][CH:31]=[CH:17][CH:18]=2)[N:15]=[C:14]2[N:10]([C:8]3[CH:7]=[CH:6][CH:5]=[C:4]([O:3][CH2:1][CH3:2])[N:9]=3)[N:11]=[C:12]([CH3:16])[C:13]=12참가 물질
6
반응물 4
생성물 2
실험 절차
Following the procedure described in Reference Example 2-4, 1-(6-ethoxy-2-pyridinyl)-3-methyl-1H-pyrazol-5-ylamine was prepared from 6-ethoxy-2-hydrazinopyridine which was prepared from 2-chloro-6-ethoxypyridine following the method described in Reference Example 2-2. Subsequently, following the methods described in Reference Example 2-5 and Example 2-1, the title compound was prepared from o-iodobenzoic acid and 1-(6-ethoxy-2-pyridinyl)-3-methyl-1H-pyrazol-5-ylamine (36% yield).
출처 및 근거
- ORD 기록
- ord-924538d461a647ff98332d649a44b220
- 출처 데이터셋
- uspto-grants-2005_09
- 특허 번호
- US06949648B2
연결된 노트
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