(4-Fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester → N1-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine

HRID 498189노트

반응식

HRID 498189 반응식
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([F:14])=[CH:10][C:9]=1[N+:15]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([F:14])=[CH:10][C:9]=1[NH2:15])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 1

HCID 59705030(4-Fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester

생성물 1

HCID 24688763N1-(tert-Butoxycarbonyl)-4-fluoro-1,2-phenylenediamine

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

The title compound was prepared from (4-fluoro-2-nitro-phenyl)-carbamic acid tert-butyl ester (Example A3) (32.54 g, 127 mmol) by hydrogenation with 10% Pd/C according to the general procedure J (method a). Obtained as a light orange solid (25.03 g).

출처 및 근거

ORD 기록
ord-074299a5d2b84d919b29a8e55ecc7135
출처 데이터셋
uspto-grants-2005_09
특허 번호
US06949542B2

반응 노트

불러오는 중…