(2-Nitro-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester → (2-Amino-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester

HRID 498198노트

반응식

HRID 498198 반응식
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([N:14]2[CH:18]=[CH:17][CH:16]=[CH:15]2)=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Pd]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([N:14]2[CH:15]=[CH:16][CH:17]=[CH:18]2)=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 1

HCID 69487086(2-Nitro-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester

생성물 1

HCID 69488996(2-Amino-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

The title compound was prepared from (2-nitro-4-pyrrol-1-yl-phenyl)-carbamic acid tert-butyl ester (Example A11) by hydrogenation with 5% Pd/C according to the general procedure J (method a). Obtained as a white solid (9.06 g).

출처 및 근거

ORD 기록
ord-b131bdfd778344a88e8cb7cbb4fe434a
출처 데이터셋
uspto-grants-2005_09
특허 번호
US06949542B2

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