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HCID 69486521, 화합물 → {5-Ethoxy-2-[3-oxo-3-(3-pyridin-4-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester

HRID 498365
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HRID 498365 반응식
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH3:16])[CH:11]=[CH:10][C:9]=1[NH2:17])([CH3:4])([CH3:3])[CH3:2].C([O:23][C:24](=O)[CH2:25][C:26](=[O:39])[C:27]1[CH:32]=[CH:31][CH:30]=[C:29]([C:33]2[CH:38]=[CH:37][N:36]=[CH:35][CH:34]=2)[CH:28]=1)(C)(C)C>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[C:12]([O:14][CH2:15][CH3:16])[CH:11]=[CH:10][C:9]=1[NH:17][C:24](=[O:23])[CH2:25][C:26](=[O:39])[C:27]1[CH:32]=[CH:31][CH:30]=[C:29]([C:33]2[CH:34]=[CH:35][N:36]=[CH:37][CH:38]=2)[CH:28]=1)([CH3:2])([CH3:4])[CH3:3]
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참가 물질

3

반응물 2

HCID 69486521HCID 69486521, 화합물HCID 694868533-Oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester

생성물 1

HCID 86589330{5-Ethoxy-2-[3-oxo-3-(3-pyridin-4-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester

실험 절차

The title compound was prepared from (2-amino-5-ethoxy-phenyl)-carbamic acid tert-butyl ester (Example J14) (193 mg, 0.76 mmol) and 3-oxo-3-(3-pyridin-4-yl-phenyl)-propionic acid tert-butyl ester (Example K2) (221 mg, 0.74 mmol) according to the general procedure M. Obtained as an off-white foam (227 mg, 65%).

출처 및 근거

ORD 기록
ord-f2b4fc72849b4583af00248d83c32f6f
출처 데이터셋
uspto-grants-2005_09
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US06949542B2

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