Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester → {4-(4-Fluoro-phenylethynyl)-2-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester | HCID 11266473 | — |
| 반응물 | [2-Amino-4-(4-fluoro-phenylethynyl)-phenyl]-carbamic acid tert-butyl ester | HCID 69486641 | — |
| 생성물 | {4-(4-Fluoro-phenylethynyl)-2-[3-oxo-3-(3-pyridin-3-yl-phenyl)-propionylamino]-phenyl}-carbamic acid tert-butyl ester | HCID 86589341 | — |
반응 단계
The title compound was prepared from [2-amino-4-(4-fluoro-phenylethynyl)-phenyl]-carbamic acid tert-butyl ester {CAS-No. [335255-58-0]} (245 mg, 0.75 mmol) and 3-oxo-3-(3-pyridin-3-yl-phenyl)-propionic acid tert-butyl ester (Example K1) (223 mg, 0.75 mmol) according to the general procedure M. Obtained as an orange foam (304 mg, 74%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06949542B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-fb49dfed6a01479c9234658eac7025a9 |
| 출처 메모 | uspto-grants-2005_09 |