Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
3-Oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl ester → {2-[3-Oxo-3-(3-pyridin-2-yl-phenyl)-propionylamino]-4-trifluoromethoxy-phenyl}-carbamic acid tert-butyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 3-Oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl ester | HCID 69489201 | — |
| 반응물 | Carbamic acid,[2-amino-4-(trifluoromethoxy)phenyl]-,1,1-dimethylethyl ester | HCID 69489489 | — |
| 생성물 | {2-[3-Oxo-3-(3-pyridin-2-yl-phenyl)-propionylamino]-4-trifluoromethoxy-phenyl}-carbamic acid tert-butyl ester | HCID 86589370 | — |
반응 단계
The title compound was prepared from (2-amino-4-trifluoromethoxy-phenyl)-carbamic acid tert-butyl ester (Example J26) (219 mg, 0.75 mmol) and 3-oxo-3-(3-pyridin-2-yl-phenyl)-propionic acid tert-butyl ester (Example K3) (223 mg, 0.75 mmol) according to the general procedure M. Obtained as a yellow solid (271 mg, 69%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06949542B2 |
| 출처 데이터셋 | uspto-grants-2005_09 |
| ORD ID | ord-77865fd418804851bf036b41d8d5d97b |
| 출처 메모 | uspto-grants-2005_09 |