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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 498427생성일: 2026년 10월 27일

Carbamic acid,n-[2-amino-5-ethyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → (2-{3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-ethyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/498427

반응식

참여 물질

역할이름HCID투입량
반응물Carbamic acid,n-[2-amino-5-ethyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 69486873—
반응물3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489240—
생성물(2-{3-[3-(2,6-Dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-5-ethyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl esterHCID 86589392—

반응 단계

The title compound was prepared from (2-amino-5-ethyl-4-trifluoromethyl-phenyl)-carbamic acid tert-butyl ester (Example J33) (152 mg, 0.5 mmol) and 3-[3-(2,6-dimethyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K15) (163 mg, 0.5 mmol) according to the general procedure M. Obtained as a white solid (185 mg, 67%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06949542B2
출처 데이터셋uspto-grants-2005_09
ORD IDord-82c4ab10f6d647e89d6c57eb199c6f71
출처 메모uspto-grants-2005_09