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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 498443생성일: 2026년 10월 26일

Carbamic acid,[2-amino-5-ethenyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl ester → (2-{3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-4-trifluoromethyl-5-vinyl-phenyl)-carbamic acid tert-butyl ester

https://huagongshe.com/reaction/498443

반응식

참여 물질

역할이름HCID투입량
반응물Carbamic acid,[2-amino-5-ethenyl-4-(trifluoromethyl)phenyl]-,1,1-dimethylethyl esterHCID 69486994—
반응물3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl esterHCID 69489307—
생성물(2-{3-[3-(2-Methyl-pyridin-4-yl)-phenyl]-3-oxo-propionylamino}-4-trifluoromethyl-5-vinyl-phenyl)-carbamic acid tert-butyl esterHCID 86589408—

반응 단계

The title compound was prepared from (2-amino-4-trifluoromethyl-5-vinyl-phenyl)-carbamic acid tert-butyl ester (Example J34) (227 mg, 0.75 mmol) and 3-[3-(2-methyl-pyridin-4-yl)-phenyl]-3-oxo-propionic acid tert-butyl ester (Example K12) (234 mg, 0.75 mmol) according to the general procedure M. Obtained as a light yellow solid (313 mg, 77%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US06949542B2
출처 데이터셋uspto-grants-2005_09
ORD IDord-3678d1c4e5164892842e2174a97c4231
출처 메모uspto-grants-2005_09