Triethylamine → HCID 59750337, 화합물
반응식
[CH3:1][C:2]1[N:3]=[C:4]([C:7]#[N:8])[S:5][CH:6]=1.[C:9](OC)(=[O:17])[C:10]1[C:11](=[CH:13][CH:14]=[CH:15][CH:16]=1)[SH:12].C(N(CC)CC)C>C1(C)C=CC=CC=1>[CH3:1][C:2]1[N:3]=[C:4]([C:7]2[S:12][C:11]3[CH:13]=[CH:14][CH:15]=[CH:16][C:10]=3[C:9](=[O:17])[N:8]=2)[S:5][CH:6]=1참가 물질
5
실험 절차
4-Methyl-1,3-thiazole-2-carbonitrile (0.27 g, 2.2 mmol) and methyl thiosalicylate (0.75 g, 4.4 mmol) were dissolved in toluene (4 ml), and triethylamine (2.0 ml, 14.3 mmol) was added thereto. The reaction mixture was refluxed for 6 hrs. After cooling, the precipitates were collected by filtration and recrystallized from ethanol to give the titled compound (0.28 g, 49%) as yellow crystals.
후처리
- temperatureThe reaction mixture was refluxed for 6 hrs
- temperatureAfter cooling
- filtrationthe precipitates were collected by filtration
- customrecrystallized from ethanol
출처 및 근거
- ORD 기록
- ord-eada794c1e674e838ccc5edbb75f8dcb
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07767665B2
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