참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,4-Butane sultone | HCID 15411 | — |
| 반응물 | Sulfolane | HCID 31347 | — |
| 반응물 | 2,3-Dimethyl-3-(4-sulfobutyl)-3H-indole-5-sulfonic acid | HCID 59366226 | — |
| 용매 | Diethyl Ether | HCID 3283 | — |
| 생성물 | 2,3-Dimethyl-1,3-bis(4-sulfobutyl)-5-sulfo-3H-indole | HCID 86646192 | 86.8% |
반응 단계
To 2,3-dimethyl-3-(4-sulfobutyl)-5-sulfo-3H-indole (10 g) was added butane sultone (30 g) and the mixture heated to 140° C. overnight. On cooling to room temperature, sulfolan (20 ml) was added and the mixture poured into diethyl ether (500 ml). The resultant precipitate was removed by filtration and dried to give the desired product (12 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US07767829B2 |
|---|
| 출처 데이터셋 | uspto-grants-2010_08 |
|---|
| ORD ID | ord-967fe06e8ce64cbea94cfa6f6fa5c726 |
|---|
| 출처 메모 | uspto-grants-2010_08 |
|---|
