(+)-Epichlorohydrin → tert-Butyl (2S)-2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylate

HRID 500482노트

반응식

HRID 500482 반응식
[C:1]([C:3]1[CH:20]=[CH:19][C:6]([O:7][CH2:8][CH:9]2[CH2:11][N:10]2[C:12]([O:14][C:15]([CH3:18])([CH3:17])[CH3:16])=[O:13])=[CH:5][CH:4]=1)#[N:2].C([C@H]1OC1)Cl>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([O:7][CH2:8][C@@H:9]2[CH2:11][N:10]2[C:12]([O:14][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:13])=[CH:19][CH:20]=1)#[N:2]

참가 물질

3

반응물 2

HCID 149428(+)-EpichlorohydrinHCID 21867670Tert-butyl 2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylate2회

생성물 1

HCID 86588968tert-Butyl (2S)-2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylate

실험 절차

The sub-title compound was prepared according to the procedures described in steps (i) to (v) above for the synthesis of tert-butyl 2-[(4-cyanophenoxy)methyl]-1-aziridinecarboxylate, but using (S)-(+)-epichlorohydrin in place of epichlorohydrin in step (i).

출처 및 근거

ORD 기록
ord-34bfae349a2b4a85b2f5c6aed1709d01
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07772229B2

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