Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(7-Chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone → (7-(2-Fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (7-Chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone | HCID 11173165 | — |
| 반응물 | 7-(2-fluoro-4-nitrophenoxy)-N,N-dimethylthieno[3,2-b]pyridine-2-carboxamide | HCID 59424475 | — |
| 생성물 | (7-(2-Fluoro-4-nitrophenoxy)thieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone | HCID 59424552 | 93% |
반응 단계
Starting from (7-chlorothieno[3,2-b]pyridin-2-yl)(pyrrolidin-1-yl)methanone (139, scheme 26) and following the procedure described above for the synthesis of compound 6 (scheme 1, example 1), title compound 193 was obtained in (93% yield). LRMS (M+1) 387.4 (100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07772247B2 |
| 출처 데이터셋 | uspto-grants-2010_08 |
| ORD ID | ord-969e09178ae74772b882fc08d8db731e |
| 출처 메모 | uspto-grants-2010_08 |