7-(2-Fluoro-4-nitrophenoxy)-2-(methylthio)thieno[3,2-b]pyridine → HCID 59424556, 화합물
반응식
[Si]([O:8][CH:9]1[CH2:12][N:11]([C:13]([C:15]2[S:23][C:22]3[C:17](=[N:18][CH:19]=[CH:20][C:21]=3Cl)[CH:16]=2)=[O:14])[CH2:10]1)(C(C)(C)C)(C)C.[F:25][C:26]1[CH:43]=[C:42]([N+:44]([O-:46])=[O:45])[CH:41]=[CH:40][C:27]=1[O:28]C1C=CN=C2C=C(SC)SC=12>>[F:25][C:26]1[CH:43]=[C:42]([N+:44]([O-:46])=[O:45])[CH:41]=[CH:40][C:27]=1[O:28][C:21]1[CH:20]=[CH:19][N:18]=[C:17]2[CH:16]=[C:15]([C:13]([N:11]3[CH2:10][CH:9]([OH:8])[CH2:12]3)=[O:14])[S:23][C:22]=12참가 물질
3
실험 절차
Starting from the amide 297 and following the procedure described above for the synthesis of compound 230 (scheme 50, example 203), title compound 298 was obtained in 39% yield as a syrup. MS (m/z): 389.05 (M+1).
출처 및 근거
- ORD 기록
- ord-886da92b1ac6488394c128af1c43c7c9
- 출처 데이터셋
- uspto-grants-2010_08
- 특허 번호
- US07772247B2