1-(3-Chlorophenyl)piperazine monohydrochloride → HCID 178455804, 화합물

HRID 501289

반응식

HRID 501289 반응식
[CH2:1]([C@H:3]1[CH2:8][CH2:7][C@H:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[CH2:15]OS(C)(=O)=O)=[O:11])[CH2:5][CH2:4]1)[CH3:2].Cl.[Cl:22][C:23]1[CH:28]=[CH:27][C:26]([N:29]2[CH2:34][CH2:33][NH:32][CH2:31][CH2:30]2)=[CH:25][CH:24]=1.Cl.ClC1C=C(N2CCNCC2)C=CC=1>>[CH2:1]([C@H:3]1[CH2:8][CH2:7][C@H:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[CH2:15][N:32]2[CH2:31][CH2:30][N:29]([C:26]3[CH:25]=[CH:24][C:23]([Cl:22])=[CH:28][CH:27]=3)[CH2:34][CH2:33]2)=[O:11])[CH2:5][CH2:4]1)[CH3:2]

참가 물질

4

반응물 3

HCID 256811-(3-Chlorophenyl)piperazine monohydrochlorideHCID 30847201-(4-Chlorophenyl)piperazine HydrochlorideHCID 178455808HCID 178455808, 화합물

생성물 1

HCID 178455804HCID 178455804, 화합물

실험 절차

Follow the procedure of Example 11e, and substitute methane sulfonic acid 2-(trans-4-ethyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester, Example 13d for 2-(trans-4-methyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester and 4-(4-chlorophenyl)-piperazine hydrochloride for 1-(3-chlorophenyl)-piperazine hydrochloride therein, to obtain the title compound LC/MS, m/z=404 (M+H)+.

출처 및 근거

ORD 기록
ord-a079947e0af14bb5a6b4cde8a050e71d
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07772252B2

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