1-(3-Chlorophenyl)piperazine monohydrochloride → HCID 178455805, 화합물

HRID 501290

반응식

HRID 501290 반응식
[CH2:1]([C@H:3]1[CH2:8][CH2:7][C@H:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[CH2:15]OS(C)(=O)=O)=[O:11])[CH2:5][CH2:4]1)[CH3:2].Cl.[Cl:22][C:23]1[CH:24]=[C:25]([N:30]2[CH2:35][CH2:34][NH:33][CH2:32][CH2:31]2)[CH:26]=[CH:27][C:28]=1[Cl:29].Cl.ClC1C=C(N2CCNCC2)C=CC=1>>[CH2:1]([C@H:3]1[CH2:8][CH2:7][C@H:6]([NH:9][C:10]([C@@H:12]2[CH2:14][C@H:13]2[CH2:15][N:33]2[CH2:32][CH2:31][N:30]([C:25]3[CH:26]=[CH:27][C:28]([Cl:29])=[C:23]([Cl:22])[CH:24]=3)[CH2:35][CH2:34]2)=[O:11])[CH2:5][CH2:4]1)[CH3:2]

참가 물질

4

반응물 3

HCID 256811-(3-Chlorophenyl)piperazine monohydrochlorideHCID 15574733Piperazine, 1-(3,4-dichlorophenyl)-, hydrochloride (1:2)HCID 178455808HCID 178455808, 화합물

생성물 1

HCID 178455805HCID 178455805, 화합물

실험 절차

Follow the procedure of Example 11e, and substitute methane sulfonic acid 2-(trans-4-ethyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester (Example 13d) for 2-(trans-4-methyl-cyclohexylcarbamoyl)-trans-cyclopropylmethyl ester and 4-(3,4-dichlorophenyl)-piperazine hydrochloride for 1-(3-chloro-phenyl)-piperazine hydrochloride therein to obtain the title compound LC/MS, m/z=438 (M+H)+.

출처 및 근거

ORD 기록
ord-7322977d984d43e7a09ed6f8dd219784
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07772252B2

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