8-(3-Aminopiperidin-1-yl)-7-(2-butynyl)-1-(2-cyanobenzyl)-6-oxo-6,7-dihydro-1H-purine-2-carbonitrile hydrochloride → 8-(3-Aminopiperidin-1-yl)-7-(2-butynyl)-6-oxo-1-(2-phenylethyl)-6,7-dihydro-1H-purine-2-carbonitrile hydrochloride
반응식
C(N1C2C(=O)N(CCC3C=CC=CC=3)C([Cl:23])=NC=2N=C1N1CCCC(NC(=O)OC(C)(C)C)C1)C#CC.Cl.[NH2:39][CH:40]1[CH2:45][CH2:44][CH2:43][N:42]([C:46]2[N:54]([CH2:55][C:56]#[C:57][CH3:58])[C:53]3[C:52](=[O:59])[N:51]([CH2:60][C:61]4[CH:66]=[CH:65][CH:64]=[CH:63][C:62]=4[C:67]#N)[C:50]([C:69]#[N:70])=[N:49][C:48]=3[N:47]=2)[CH2:41]1>>[ClH:23].[NH2:39][CH:40]1[CH2:45][CH2:44][CH2:43][N:42]([C:46]2[N:54]([CH2:55][C:56]#[C:57][CH3:58])[C:53]3[C:52](=[O:59])[N:51]([CH2:60][CH2:61][C:66]4[CH:65]=[CH:64][CH:63]=[CH:62][CH:67]=4)[C:50]([C:69]#[N:70])=[N:49][C:48]=3[N:47]=2)[CH2:41]1참가 물질
3
반응물 2
생성물 1
실험 절차
The title compound was synthesized by using t-butyl [1-[7-(2-butynyl)-2-chloro-6-oxo-1-(2-phenylethyl)-6,7-dihydro-1H-purin-8-yl]piperidin-3-yl]carbamate according to the method described in Example 242 (f) and (g).