참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 1,1-Dibromoethane | HCID 11201 | — |
| 반응물 | Zinc | HCID 23994 | — |
| 반응물 | Methyl 2-(bromomethyl)benzoate | HCID 2734813 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | HCID 178497629 | HCID 178497629 | — |
반응 단계
Under atmosphere of argon, to a solution of zinc powder (1.89 g) in anhydrous THF (15 ml) was added dibromoethane (116 ul) and the mixture was stirred for five minutes at 60° C. To the reaction mixture was added a solution of 2-bromomethylbenzoic acid methyl ester (4.42 g) in anhydrous THF (15 ml) over a period of 30 minutes at 0° C. and the mixture was stirred for 2 hours at the temperature to give a 2-carbomethoxybenzylzinc (II) bromide (benzyl zinc) solution.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06710205B2 |
|---|
| 출처 데이터셋 | uspto-grants-2004_03 |
|---|
| ORD ID | ord-3d85f2e4c29643f2af3cd20c5f177c58 |
|---|
| 출처 메모 | uspto-grants-2004_03 |
|---|
