3-Chloro-2-methylaniline → N-(4-Bromo-3-chloro-2-methylphenyl)acetamide

반응식

[Cl:1]C1C(C)=C(C=CC=1)N.C1(NC(=O)C)C2CCCCC=2C=CC=1.[Br:24][C:25]1[C:34]2CCC[CH2:30][C:29]=2[C:28]([NH:35][C:36](=[O:38])[CH3:37])=[CH:27][CH:26]=1>>[Br:24][C:25]1[CH:26]=[CH:27][C:28]([NH:35][C:36](=[O:38])[CH3:37])=[C:29]([CH3:30])[C:34]=1[Cl:1]

참가 물질

반응물 3

HCID 68943-Chloro-2-methylaniline

HCID 2320651-Acetamido-5,6,7,8-tetrahydronaphthalene

HCID 12710300N-(4-Bromo-5,6,7,8-tetrahydronaphthalen-1-yl)-acetamide

생성물 1

HCID 86376N-(4-Bromo-3-chloro-2-methylphenyl)acetamide수율 96%

실험 절차

The title compound was prepared (2.75 g, 96% yield) from commercially available 3-chloro-2-methylaniline by procedures analogous to those described in Experiment 2A and 2B.

출처 및 근거

ORD 기록: ord-673d5d16067c40da8b97fd953d0234e1
출처 데이터셋: uspto-grants-2010_08
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07772267B2

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