Potassium Bromide → HCID 178480189, 화합물

HRID 50270노트

반응식

HRID 50270 반응식
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([CH2:9][CH2:10][C:11](O)=O)=[CH:5][CH:4]=1)#[N:2].[C:14]1([N:20]([CH2:32][CH2:33][C:34]2[NH:38][N:37]=[N:36][N:35]=2)[C:21](=[O:31])[C:22]2[CH:27]=[CH:26][C:25]([NH:28][CH3:29])=[C:24]([NH2:30])[CH:23]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[K+].[Br-]>>[C:14]1([N:20]([CH2:32][CH2:33][C:34]2[NH:38][N:37]=[N:36][N:35]=2)[C:21]([C:22]2[CH:27]=[CH:26][C:25]3[N:28]([CH3:29])[C:11]([CH2:10][CH2:9][C:6]4[CH:5]=[CH:4][C:3]([C:1]#[N:2])=[CH:8][CH:7]=4)=[N:30][C:24]=3[CH:23]=2)=[O:31])[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

참가 물질

4

반응물 3

HCID 253877Potassium BromideHCID 93617423-(4-Cyanophenyl)-propionic acidHCID 178482173HCID 178482173, 화합물

생성물 1

HCID 178480189HCID 178480189, 화합물수율 67%

실험 절차

Prepared analogously to Example 25c from 3-(4-cyanophenyl)propionic acid and 3-amino-4-methylaminobenzoic acid-N-phenyl-N-[2-(1H-tetrazol-5-yl)ethyl]amide. Yield: 67% of theory; IR mass spectrum (KBr): characteristic bands at 3439.5 cm−1 (N—H); 2235.5 cm−1 (C≡N) 1631.6 cm−1 (C═O).

출처 및 근거

ORD 기록
ord-d5100bc99d114f7782c186aa989b73fa
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06710055B2

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