Oxalyl chloride → 3,5-Di-t-butylbenzoyl chloride

HRID 502790

반응식

HRID 502790 반응식
[C:1](Cl)(=O)[C:2]([Cl:4])=[O:3].[C:7]([C:11]1[CH:12]=C([CH:17]=[C:18]([C:20]([CH3:23])([CH3:22])[CH3:21])[CH:19]=1)C(O)=O)([CH3:10])([CH3:9])[CH3:8]>CN(C)C=O.ClCCl>[C:20]([C:18]1[CH:17]=[C:1]([CH:12]=[C:11]([C:7]([CH3:10])([CH3:9])[CH3:8])[CH:19]=1)[C:2]([Cl:4])=[O:3])([CH3:23])([CH3:22])[CH3:21]

참가 물질

5

반응물 2

HCID 65578Oxalyl chlorideHCID 853393,5-Bis(tert-butyl)benzoic acid

생성물 1

HCID 118176223,5-Di-t-butylbenzoyl chloride

시약·촉매·용매 2

HCID 6228Dimethylformamide촉매HCID 6344Dichloromethane용매

실험 절차

Oxalyl chloride (0.542 g, 0.37 ml, 4.27 mmol) was added dropwise to a solution of 3,5-di-tert-butylbenzoic acid (0.200 g, 0.853 mmol) and dichloromethane (4 ml). N,N-Dimethylformamide (1 drop) was added and the colorless solution stirred at RT for 3 h. The solution was concentrated to afford 3,5-di-tert-butylbenzoyl chloride as a yellow oil.

후처리

  1. concentrationThe solution was concentrated

출처 및 근거

ORD 기록
ord-992d23101f33403e8fa8cd7dad5e4beb
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07776869B2

연결된 노트

불러오는 중…