Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide → 1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane diacetate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide | HCID 19088834 | — |
| 반응물 | Methanol--water (1/1) | HCID 22242641 | — |
| 생성물 | 1,12-Bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane diacetate | HCID 67867054 | — |
반응 단계
30.0 g (0.048 mol) of 1,12-bis(2-amino-3,4,5,6-tetrahydropyrimidyl)dodecane dihydroiodide in 300 ml of methanol/water (1:1) were filtered through a column containing 250 g of ion exchanger (OH- form). The free guanidine base obtained after working up was dissolved in methanol and converted into the diacetate with excess glacial acetic acid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05242948 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-62caf7e77d574b0eacf847ea9cbf3833 |
| 출처 메모 | uspto-grants-1993_09 |