3,3-Dimethylbutanoyl chloride → 5,7-DIMETHYL-3-(4-[2-[({[(4-METHYLPHENYL)SULFONYL]AMINO}CARBONYL)AMINO]ETHYL}PHENYL)-2-NEOPENTYL-3H-IMIDAZO[4,5-b]PYRIDINE

HRID 50425

반응식

HRID 50425 반응식
C(C1[N:13]([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:25][S:26]([C:29]3[CH:34]=[CH:33][C:32]([CH3:35])=[CH:31][CH:30]=3)(=[O:28])=[O:27])=[O:24])=[CH:16][CH:15]=2)[C:6]2=[N:7][C:8]([CH3:12])=[CH:9][C:10]([CH3:11])=[C:5]2[N:4]=1)C.[C:36]([CH2:40][C:41](Cl)=O)([CH3:39])([CH3:38])[CH3:37]>>[CH3:12][C:8]1[N:7]=[C:6]2[N:13]([C:14]3[CH:15]=[CH:16][C:17]([CH2:20][CH2:21][NH:22][C:23]([NH:25][S:26]([C:29]4[CH:30]=[CH:31][C:32]([CH3:35])=[CH:33][CH:34]=4)(=[O:27])=[O:28])=[O:24])=[CH:18][CH:19]=3)[C:41]([CH2:40][C:36]([CH3:37])([CH3:38])[CH3:39])=[N:4][C:5]2=[C:10]([CH3:11])[CH:9]=1

참가 물질

3

반응물 2

HCID 815143,3-Dimethylbutanoyl chlorideHCID 99353672-ETHYL-5,7-DIMETHYL-3-(4-{2-[({[(4-METHYLPHENYL)SULFONYL]AMINO}CARBONYL)AMINO]ETHYL}PHENYL)-3H-IMIDAZO[4,5-b]PYRIDINE

생성물 1

HCID 218756245,7-DIMETHYL-3-(4-[2-[({[(4-METHYLPHENYL)SULFONYL]AMINO}CARBONYL)AMINO]ETHYL}PHENYL)-2-NEOPENTYL-3H-IMIDAZO[4,5-b]PYRIDINE

실험 절차

The title compound was prepared according to the procedure described in step 5 of Example 1 from 2-{4-[(3-amino-4,6-dimethyl-2-pyridinyl)amino]phenyl]ethanol (step 4 of Example 1) and tert-butylacetyl chloride.

출처 및 근거

ORD 기록
ord-061b30b5d253412e930b1e05f200a656
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06710054B2

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