5-Chlorothiophene-2-Sulfonamide → 3-(4-{2-[({[(5-CHLORO-2-THIENYL)SULFONYL]AMINO}CARBONYL)AMINO]ETHYL}PHENYL)-2-ETHYL-5,7-DIMETHYL-3H-IMIDAZO[4,5-b]PYRIDINE

HRID 50430

반응식

HRID 50430 반응식
C1(C2C=CC=CC=2)C=CC(S(N[C:11]([NH:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([N:22]3[C:26]4=[N:27][C:28]([CH3:32])=[CH:29][C:30]([CH3:31])=[C:25]4[N:24]=[C:23]3[CH2:33][CH3:34])=[CH:18][CH:17]=2)=[O:12])(=O)=O)=CC=1.[Cl:41][C:42]1[S:46][C:45]([S:47]([NH2:50])(=[O:49])=[O:48])=[CH:44][CH:43]=1>>[Cl:41][C:42]1[S:46][C:45]([S:47]([NH:50][C:11]([NH:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([N:22]3[C:26]4=[N:27][C:28]([CH3:32])=[CH:29][C:30]([CH3:31])=[C:25]4[N:24]=[C:23]3[CH2:33][CH3:34])=[CH:18][CH:17]=2)=[O:12])(=[O:49])=[O:48])=[CH:44][CH:43]=1

참가 물질

3

반응물 2

HCID 12413015-Chlorothiophene-2-SulfonamideHCID 218756193-{4-[2-({[(4-biphenylsulfonyl)amino]carbonyl}amino)ethyl]phenyl}-2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine

생성물 1

HCID 218760843-(4-{2-[({[(5-CHLORO-2-THIENYL)SULFONYL]AMINO}CARBONYL)AMINO]ETHYL}PHENYL)-2-ETHYL-5,7-DIMETHYL-3H-IMIDAZO[4,5-b]PYRIDINE

실험 절차

The title compound was prepared according to the procedure described in step 2 of Example 18 from phenyl 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethylcarbamate (step 1 of Example 18) and 5-chloro-2-thiophenesulfonamide.

출처 및 근거

ORD 기록
ord-a6b92094015e48e5b36d1dd94daf3473
출처 데이터셋
uspto-grants-2004_03
특허 번호
US06710054B2

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