Pyridine sulfonamide → 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl 2-pyridinylsulfonylcarbamate
반응식
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7]([NH2:10])(=[O:9])=[O:8].N1C=CC=C(S(N[C:21](=[O:47])[O:22][CH2:23][CH2:24][C:25]2[CH:30]=[CH:29][C:28]([N:31]3[C:35]4[CH:36]=[C:37]([Cl:44])[C:38]([C:40]([F:43])([F:42])[F:41])=[CH:39][C:34]=4[N:33]=[C:32]3[CH2:45][CH3:46])=[CH:27][CH:26]=2)(=O)=O)C=1>>[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[S:7]([NH:10][C:21](=[O:47])[O:22][CH2:23][CH2:24][C:25]1[CH:26]=[CH:27][C:28]([N:31]2[C:35]3[CH:36]=[C:37]([Cl:44])[C:38]([C:40]([F:41])([F:43])[F:42])=[CH:39][C:34]=3[N:33]=[C:32]2[CH2:45][CH3:46])=[CH:29][CH:30]=1)(=[O:9])=[O:8]참가 물질
3
실험 절차
The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-pyridinesulfonamide (Naito, T.; et al., Chem. Pharm. Bull., 1955, 3, 38) and 2-[4-(2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)phenyl]ethylcarbamate (step 1 of Example 243).
출처 및 근거
- ORD 기록
- ord-ef7998a4244b4be9976af6216d86b046