Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-chloro-N,N-dimethylacetamide → 2-{6-Chloro-3-[4-(2,6-dimethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N,N-dimethyl-acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-chloro-N,N-dimethylacetamide | HCID 75886 | — |
| 반응물 | (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone | HCID 16062188 | — |
| 생성물 | 2-{6-Chloro-3-[4-(2,6-dimethoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-N,N-dimethyl-acetamide | HCID 15602697 | — |
반응 단계
Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone (preparation described herein), with commercially available 2-chloro-N,N-dimethyl-acetamide gave the title compound.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07781436B2 |
| 출처 데이터셋 | uspto-grants-2010_08 |
| ORD ID | ord-aa37a6582d6f45eca029cfb026bbeda4 |
| 출처 메모 | uspto-grants-2010_08 |