Ethanone, 2-chloro-1-(2-pyridinyl)- (9CI) → HCID 16062189, 화합물

HRID 505088

반응식

HRID 505088 반응식
[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]([N:13]3[CH2:18][CH2:17][CH:16]([C:19]4[C:24]([O:25][CH3:26])=[CH:23][CH:22]=[CH:21][C:20]=4[O:27][CH3:28])[CH2:15][CH2:14]3)=[O:12])=[CH:7][NH:8]2)=[CH:4][CH:3]=1.Cl[CH2:30][C:31]([C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=1)=[O:32]>>[Cl:1][C:2]1[CH:10]=[C:9]2[C:5]([C:6]([C:11]([N:13]3[CH2:14][CH2:15][CH:16]([C:19]4[C:24]([O:25][CH3:26])=[CH:23][CH:22]=[CH:21][C:20]=4[O:27][CH3:28])[CH2:17][CH2:18]3)=[O:12])=[CH:7][N:8]2[CH2:30][C:31]([C:33]2[CH:38]=[CH:37][CH:36]=[CH:35][N:34]=2)=[O:32])=[CH:4][CH:3]=1

참가 물질

3

반응물 2

HCID 12215232Ethanone, 2-chloro-1-(2-pyridinyl)- (9CI)HCID 16062188(6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone

생성물 1

HCID 16062189HCID 16062189, 화합물

실험 절차

Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone (preparation described herein), with commercially available 2-chloro-1-pyridin-2-yl-ethanone gave the title compound.

출처 및 근거

ORD 기록
ord-f9d0b52984524da9847c82b1eae2ad40
출처 데이터셋
uspto-grants-2010_08
특허 번호
US07781436B2

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