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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 505089생성일: 2026년 10월 27일

4-(Chloromethyl)pyridine → (6-Chloro-1-pyridin-4-ylmethyl-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone

https://huagongshe.com/reaction/505089

반응식

참여 물질

역할이름HCID투입량
반응물4-(Chloromethyl)pyridineHCID 74571—
반응물(6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanoneHCID 16062188—
생성물(6-Chloro-1-pyridin-4-ylmethyl-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanoneHCID 16062190—

반응 단계

Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2,6-dimethoxy-phenyl)-piperidin-1-yl]-methanone (preparation described herein), with commercially available 4-chloromethyl-pyridine gave the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07781436B2
출처 데이터셋uspto-grants-2010_08
ORD IDord-114d4b471ac54492bfe51896e2d2e440
출처 메모uspto-grants-2010_08