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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 505106생성일: 2026년 10월 26일

2-Chloro-1-(4-methylpiperazin-1-yl)ethanone → 2-{6-Chloro-3-[4-(2-isopropoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-1-(4-methyl-piperazin-1-yl)-ethanone

https://huagongshe.com/reaction/505106

반응식

참여 물질

역할이름HCID투입량
반응물2-Chloro-1-(4-methylpiperazin-1-yl)ethanoneHCID 818173—
반응물(6-chloro-1H-indol-3-yl)-[4-(2-isopropoxy-phenyl)-piperidin-1-yl]-methanoneHCID 59429630—
생성물2-{6-Chloro-3-[4-(2-isopropoxy-phenyl)-piperidine-1-carbonyl]-indol-1-yl}-1-(4-methyl-piperazin-1-yl)-ethanoneHCID 16062575—

반응 단계

Following general procedure II, the alkylation of (6-chloro-1H-indol-3-yl)-[4-(2-isopropoxy-phenyl)-piperidin-1-yl]-methanone (preparation described herein), with (commercially available) 2-chloro-1-(4-methyl-piperazin-1-yl)-ethanone gave the title compound.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07781436B2
출처 데이터셋uspto-grants-2010_08
ORD IDord-84e642fd5c4f42e6abe56fa1819d010a
출처 메모uspto-grants-2010_08